Based on 40 studies which compare combinations of behavioural
support and medications with groups receiving usual care or less
behavioural support, the Cochrane review concludes that combined
pharmacotherapy and behavioural support significantly increases
smoking cessation.
Stop smoking medications effective in populations
according to ITC study

Results from a new ITC study indicate that cessation rates are
higher among those using stop smoking medications compared to those
attempting to quit without medication. These findings are
consistent with the findings of clinical trials. Despite the
advantage gained by using medications, however, many who make quit
attempts do so without medications. Thus, in theory, population
quit rates could be increased by promoting use of effective
medications, even if among those using these medications, relapse
to smoking remains the norm.
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